A novel microfluidic system for the rapid analysis of protein thermal stability.
نویسندگان
چکیده
We describe a simple microfluidic device for the rapid analysis of protein thermal stability using a novel imaging method. The change in UV absorption upon thermal denaturation or aggregation of proteins is used to get a spatial image of proteins' folding or aggregation state along a linear temperature gradient.
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ورودعنوان ژورنال:
- The Analyst
دوره 139 11 شماره
صفحات -
تاریخ انتشار 2014